ea0081p479 | Thyroid | ECE2022
Bruno Carmine
, Vergani Edoardo
, Capobianco Emmanuele
, Anna Nicolazzi Maria
, Maria Rita Favuzzi Angela
, Silvestrini Andrea
, Meucci Elisabeta
, Panocchia Nicola
, Mancini Antonio
Non-thyroidal-illness syndrome (NTIS) is present in chronic diseases and considered an adaptive mechanism. However oxidative stress is linked to NTIS in a vicious circle, due to deiodinases alteration and negative effects of low T3 on antioxidant levels or activity. Moreover there is a tissue-specific thyroid hormone transport, receptor binding and hormone metabolism. Muscle is one of the main targets of thyroid hormone; on the other hand, Irisin is a novel discovered myokine ...